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PubMed COVID-19 Clinical Care

821 - 830 of 44979 results found

SARS-CoV-2 and UPS with potentials for therapeutic interventions

Date
Friday, March 15, 2024 - 4:00 AM
Description
The Ubiquitin proteasome system (UPS), an essential eukaryotic/host/cellular post-translational modification (PTM), plays a critical role in the regulation of diverse cellular functions including regulation of protein stability, immune signaling

2-Bromopalmitate depletes lipid droplets to inhibit viral replication

Date
Friday, March 15, 2024 - 4:00 AM
Description
The global impact of emerging viral infections emphasizes the urgent need for effective broad-spectrum antivirals. The cellular organelle, lipid droplet (LD), is utilized by many types of viruses for replication, but its reduction does not affect