PubMed COVID-19 Clinical Care

CRISPR-Cas13-mediated viral genome targeting is a novel strategy for defending against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Here, we generated mRNA-encoded Cas13b targeting the open reading frame 1b (ORF1b) region to

Brazil was one of the countries most impacted by the COVID-19 pandemic, with a cumulative total of nearly 700,000 deaths by early 2023. The country's federative units were unevenly affected by the pandemic and adopted mitigation measures of different

Adolescents in secondary schools have limited susceptibility to the SARS-COV-2 virus, but paradoxically are considered to be carrying the highest psychosocial burden during this pandemic. The aim of our European multi-country qualitative research was

The social contact rate has influenced the transmission of COVID-19, with more social contact resulting in more contagion cases. We chose 18 countries with the most confirmed cases in the first 200 days after the Wuhan lockdown. This was the first

CONCLUSIONS: The COVID-19 pandemic increased the bystander CPR rate in association with enhanced DA-CPR attempts and improved the outcomes of elderly patients with OHCAs.

Little is known about the experiences of Filipino Americans with type 2 diabetes regarding their self-management during the early phase of the COVID-19 pandemic. We conducted a qualitative research study using semistructured interviews. In total, 19

Objectives: In this research, we examined the academic and psychological coping of post-secondary students during the early stages of COVID-19. The main goal was to investigate correlations involving self- compassion, spirituality, psychological

CONCLUSIONS: Findings of this research highlight the negative and long-lasting impact of traumatic events experienced on women's psychological health and psychosocial functioning during the perinatal period, as well as perinatal women's unmet

This study evaluates the functional capacity of CD4^(+) and CD8^(+) terminally-differentiated effector (T(EMRA)), central memory (T(CM)), and effector memory (T(EM)) cells obtained from the volunteers vaccinated with an aluminum-adjuvanted

CONCLUSIONS: Our data show that the proposed algorithm represents a valid alternative diagnostic approach to increase testing efficiency during future pandemic phases with high positivity rates (>20%) and elevated numbers of RT-PCR test requests.