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PubMed COVID-19 Clinical Care

36331 - 36340 of 44979 results found

NAD+ metabolism-based immunoregulation and therapeutic potential

Date
Wednesday, May 10, 2023 - 4:00 AM
Description
Nicotinamide adenine dinucleotide (NAD^(+)) is a critical metabolite that acts as a cofactor in energy metabolism, and serves as a cosubstrate for non-redox NAD^(+)-dependent enzymes, including sirtuins, CD38 and poly(ADP-ribose) polymerases. NAD^(+)

Excess mortality and COVID-19 deaths in Italy: A peak comparison study

Date
Wednesday, May 10, 2023 - 4:00 AM
Description
During a sanitary crisis, excess mortality measures the number of all-cause deaths, beyond what we would have expected if that crisis had not occurred. The high number of COVID-19 deaths started a debate in Italy with two opposite positions: those