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PubMed COVID-19 Clinical Care

14091 - 14100 of 44979 results found

Generation of focused drug molecule library using recurrent neural network

Date
Monday, November 06, 2023 - 4:00 AM
Description
CONTEXT: With the wide application of deep learning in drug research and development, de novo molecular design methods based on recurrent neural network (RNN) have strong advantages in drug molecule generation. The RNN model can be used to learn the

Immune imprinting and next-generation coronavirus vaccines

Date
Monday, November 06, 2023 - 4:00 AM
Description
Vaccines based on historical virus isolates provide limited protection from continuously evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill over between animals and humans. Despite repeated booster

Neutron reflection and scattering in characterising peptide assemblies

Date
Monday, November 06, 2023 - 4:00 AM
Description
Self-assemblies of de novo designed short peptides at interface and in bulk solution provide potential platforms for developing applications in many medical and technological areas. However, characterising how bioinspired supramolecular