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PubMed COVID-19 Clinical Care

12671 - 12680 of 44979 results found

PER2 gene and its association with sleep-related disorders: A review

Date
Sunday, November 19, 2023 - 4:00 AM
Description
The natural circadian rhythm in an individual governs the sleep-wake cycle over 24 hours. Disruptions in this internal cycle can lead to major health hazards and sleep disorders. Reports suggest that at least 50% of people worldwide suffer from sleep

Quality of the sample-based RNA determines the real-time RT-PCR results in the laboratory diagnosis of COVID-19

Date
Sunday, November 19, 2023 - 4:00 AM
Description
Effect of the quality of sample-based RNA on COVID-19 real-time RT-PCR results was investigated. The purity of the extracts was dependent on the extraction method (P<0.0001) and affected the test interpretations (P = 0.002). Gross RNA concentration negatively correlated with Ct values (P < 0.0001). The presence of impurities contributed to inconclusive test results.

Artificial COVID-19 T-Cell Immunogen

Date
Saturday, November 18, 2023 - 4:00 AM
Description
An artificial T-cell immunogen consisting of conserved fragments of different proteins of the SARS-CoV-2 virus and its immunogenic properties were studied in BALB/c mice. To create a T-cell immunogen, we used an approach based on the design of