PubMed COVID-19 Clinical Care
4951 - 4960 of 44979 results found
Change of epidemiological characteristics of four respiratory viral infections in children before and during COVID-19 pandemic
Description
CONCLUSIONS: Public health interventions for different pathogens are maximally effective. While positive rates for ADV, FLUA and FLUB decreased during the COVID-19 pandemic period, positive rates for RSV remained similar. In RSV and FLUA, off-season
In vitro broad-spectrum antiviral activity of MIT-001, a mitochondria-targeted reactive oxygen species scavenger, against severe acute respiratory syndrome coronavirus 2 and multiple zoonotic viruses
Description
The COVID-19 pandemic caused by SARS-CoV-2 becomes a serious threat to global health and requires the development of effective antiviral therapies. Current therapies that target viral proteins have limited efficacy with side effects. In this study
Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement
Description
The virally encoded 3C-like protease (3CL^(pro)) is a well-validated drug target for the inhibition of coronaviruses including Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Most inhibitors of 3CL^(pro) are peptidomimetic, with a γ
Shaping the future of antiviral Treatment: Spotlight on Nucleobase-Containing drugs and their revolutionary impact
Description
Nucleobases serve as essential molecular frameworks present in both natural and synthetic compounds that exhibit notable antiviral activity. Through molecular modifications, novel nucleobase-containing drugs (NCDs) have been developed, exhibiting
GIFNet: an effective global infection feature network for automatic COVID-19 lung lesions segmentation
Description
The ongoing COronaVIrus Disease 2019 (COVID-19) pandemic carried by the SARS-CoV-2 virus spread worldwide in early 2019, bringing about an existential health catastrophe. Automatic segmentation of infected lungs from COVID-19 X-ray and computer
Turkish nurses' psychological resilience and burnout levels during the COVID-19 pandemic: A correlational study
Description
CONCLUSIONS: In order to increase the quality of patient care/treatment, nurse managers need to reduce nurses' burnout and increase their psychological resilience. Nurses are recommended to adopt a healthy lifestyle, organize training programmes and
Implementing decision aids for cardiovascular disease prevention: stakeholder interviews and case studies in Australian primary care
Description
CONCLUSIONS: This research identified a wide range of feasible strategies to implement decision aids for CVD risk assessment and management. The findings will inform the translation of new CVD guidelines in primary care. Future research will use
Clinical analysis of COVID-19 in patients with preexisting interstitial lung abnormalities
Description
Objective: To describe the clinical characteristics of SARS-CoV-2 infected patients with interstitial lung abnormalities (ILA) during the COVID-19 pandemic. Methods: We respectively enrolled ILA patients who had been regularly followed up in Peking
Statin use and clinical outcomes in hospitalized COVID-19 patients: A retrospective analysis in Riyadh, Saudi Arabia
Description
CONCLUSION: Statins are associated with a higher risk of mortality and morbidity among patients hospitalized for COVID-19.
