PubMed COVID-19 Clinical Care

No abstract

CONCLUSION: The study findings indicated the potential role of miR-223 and the dysregulation of NLRP3 inflammasome followed by IL-1β, as a regulatory factor in the pathogenesis of COVID-19, like that in other inflammatory diseases.

As the world is experiencing the pandemic of SARS-CoV-2 responsible for COVID-19, one can wonder if members of other family of viruses could possibly emerge. Can such viruses establish a worldwide distribution with consequences similar to SARS-CoV-2

SARS-CoV-2 nucleocapsid protein (N-protein) rises early in body fluids during infection and has recently been identified as a direct inducer for lung injury. However, the signal mechanism of N-protein in lung inflammatory response remains poorly

Businesses associated with information technology and telecommunications have increased in importance since the start of the COVID-19 pandemic due to transformations in working and buying. Currently, universities in Latin America are making efforts

CONCLUSION: This study met its aims in confirming the acceptability of the study protocol and suggested that intervention for MPE improved fatigue levels. However, the sample size was small and a further larger statistically powered study should be

CONCLUSIONS AND RELEVANCE: This cohort study of low-frequency variants resistant to nirmatrelvir-ritonavir found that these variants were very rare in samples from patients with SARS-CoV-2, suggesting that selection of these variants by nirmatrelvir

PURPOSE OF REVIEW: To describe the current state of knowledge regarding COVID-19 in patients with systemic lupus erythematosus (SLE). We focus on (i) SARS-CoV-2 vaccination uptake, immunogenicity and safety, and (ii) outcomes of COVID-19 in patients

The global decline in vaccine coverage led the World Health Organization (WHO) in 2019 to define vaccine hesitation as one of the world's top ten threats to public health. In Brazil, the drop in vaccination coverage began in 2012, increasing from

CONCLUSIONS: Despite a weak evidence base, the research suggests that combined mitigation measures can help to reduce SARS-CoV-2 transmission but are unlikely to prevent outbreaks entirely. Evidence suggests that community prevalence may modify the