PubMed COVID-19 Clinical Care
44141 - 44150 of 44979 results found
Structural diversity of the SARS-CoV-2 Omicron spike
Description
Aided by extensive spike protein mutation, the SARS-CoV-2 Omicron variant overtook the previously dominant Delta variant. Spike conformation plays an essential role in SARS-CoV-2 evolution via changes in receptor binding domain (RBD) and neutralizing
Olfactory Dysfunction in Patients With Coronavirus Disease 2019: A Review
Description
The coronavirus disease 2019 (COVID-19) pandemic is wreaking havoc on public-health and economic systems worldwide. Among the several neurological symptoms of patients with COVID-19 reported in clinical practice, olfactory dysfunction (OD) is the
Animal models for SARS-CoV-2 and SARS-CoV-1 pathogenesis, transmission and therapeutic evaluation
Description
There is a critical need to develop animal models to alleviate vaccine and drug development difficulties against zoonotic viral infections. The coronavirus family, which includes severe acute respiratory syndrome coronavirus 1 and severe acute
Targeted therapies for unresectable stage III non-small cell lung cancer
Description
Until recently, the standard treatment in unresectable stage III non-small cell lung cancer was concurrent chemoradiotherapy, but often with dismal outcome. The introduction of consolidation treatment with immune checkpoint inhibitors has shifted the
Systemic treatments for thymic tumors: a narrative review
Description
Thymic epithelial tumours (TETs) are rare tumours originating from the thymus. Considering the rarity of this disease, the management of TETs is still challenging and difficult. In fact, all the worldwide clinical practice guidelines are based on
COMMENTARYOmicron (B.1.1.529) variant of SARS-CoV-2- Concerns, challenges and recent updates
Description
The emergence of Omicron (B.1.1.529) variant was documented with a steep increase of COVID-19 cases in South Africa, and was classified as variant of concern on 26^(th) November, 2021 by the WHO. This highly muted variant is found to be more
Variant to function mapping at single-cell resolution through network propagation
Description
With burgeoning human disease genetic associations and single-cell genomic atlases covering a range of tissues, there are unprecedented opportunities to systematically gain insights into the mechanisms of disease-causal variation. However, sparsity
COVID-19 Knowledge, Beliefs, and Behavior Among Patients in a Safety-Net Health System
Description
Examine COVID-19 knowledge, concerns, behaviors, stress, and sources of information among patients in a safety-net health system in Louisiana. Research assistants surveyed participants via structured telephone interviews from April to October 2020
