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PubMed COVID-19 Clinical Care

38951 - 38960 of 44979 results found

Exploring QSAR models for activity-cliff prediction

Date
Tuesday, April 18, 2023 - 4:00 AM
Description
INTRODUCTION AND METHODOLOGY: Pairs of similar compounds that only differ by a small structural modification but exhibit a large difference in their binding affinity for a given target are known as activity cliffs (ACs). It has been hypothesised that

Plasmablasts in previously immunologically naïve COVID-19 patients express markers indicating mucosal homing and secrete antibodies cross-reacting with SARS-CoV-2 variants and other beta-coronaviruses

Date
Tuesday, April 18, 2023 - 4:00 AM
Description
Antigen-specific class-switched antibodies are detected at the same time or even before IgM in serum of non-vaccinated individuals infected with SARS-CoV-2. These derive from the first wave of plasmablasts formed. The phenotype and specificity of

Association of COVID-19 Infection With Incident Diabetes

Date
Tuesday, April 18, 2023 - 4:00 AM
Description
CONCLUSIONS AND RELEVANCE: In this cohort study, SARS-CoV-2 infection was associated with a higher risk of diabetes and may have contributed to a 3% to 5% excess burden of diabetes at a population level.