Social support during pregnancy and the risk of postpartum depression in Polish women: A prospective study

Saturday, March 23, 2024 - 4:00 AM

Social support has been proposed as an important determinant of women's physical and emotional well-being during pregnancy and after childbirth. Our study aimed to examine the association between the risk of postpartum depression (PPD) and perceived

Surface engineering of lipid nanoparticles: targeted nucleic acid delivery and beyond

Friday, March 22, 2024 - 4:00 AM

Harnessing surface engineering strategies to functionalize nucleic acid-lipid nanoparticles (LNPs) for improved performance has been a hot research topic since the approval of the first siRNA drug, patisiran, and two mRNA-based COVID-19 vaccines

Surge Capacity of Taipei's Regional Emergency Medical System during COVID-19: A System Dynamics Approach

Friday, March 22, 2024 - 4:00 AM

CONCLUSIONS: We combined data regarding the availability of ventilators, physicians, nurses, specialized beds, and general acute care beds in our simulations. Thus, our simulations, with support from a well-established regional command and management

Short-term exposure to air pollution and hospital admission after COVID-19 in Catalonia: the COVAIR-CAT study

Friday, March 22, 2024 - 4:00 AM

CONCLUSIONS: Our study suggests positive associations between NO2, PM2.5 and PM10 and hospitalization risk among individuals diagnosed with COVID-19 during the second wave. Cumulative hazard ratios were largely driven by exposure on the same day as

SARS-CoV-2 Persistence in Immunocompromised Patients Requiring Treatment With Convalescent Plasma: A Case Report

Friday, March 22, 2024 - 4:00 AM

Severe acute respiratory syndrome-2 (SARS-CoV-2) infection in immunocompromised patients presents a challenge, as patients with such conditions may have severe courses. Identifying modalities to shorten the course or lessen the severity of infection

Stressors, emotions, and social support systems among respiratory nurses during the Omicron outbreak in China: a qualitative study

Friday, March 22, 2024 - 4:00 AM

CONCLUSION: Nursing managers should be attentive to frontline nurses' needs and occupational stress during novel coronavirus disease 2019 (COVID-19) outbreaks. Management should strengthen psychological and social support systems, optimize nursing

Safety, efficacy, and pharmacokinetics of nirmatrelvir and ritonavir in patients with severe COVID-19 and renal impairment: A case report

Friday, March 22, 2024 - 4:00 AM

Nirmatrelvir/ritonavir (N/r) has received emergency use authorization for mild-to-moderate COVID-19 treatment in adult and pediatric patients (aged and weighing at least 12 years and 40 kg, respectively) presenting positive direct SARS-CoV-2 viral

Synthesis, molecular docking analysis, molecular dynamic simulation, ADMET, DFT, and drug likeness studies: Novel Indeno[1,2-b]pyrrol-4(1H)-one as SARS-CoV-2 main protease inhibitors

Friday, March 22, 2024 - 4:00 AM

BACKGROUND: The COVID-19 pandemic began in 2019 as a result of the advent of a novel coronavirus, SARS-CoV-2. At present, there are a limited number of approved antiviral agents for the treatment of COVID-19. Remdesivir, Molnupiravir, and Paxlovid

Should we be afraid of long-term cardiac consequences in children with multisystem inflammatory syndrome? Experience from subsequent waves of COVID-19

Friday, March 22, 2024 - 4:00 AM

The purpose of the study was to assess and compare short- and long-term cardiac complications of the multisystem inflammatory syndrome in children (MIS-C) by predominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants throughout

Suicidal ideation, perception of personal safety, and career regret among emergency medicine residents during the COVID-19 pandemic

Friday, March 22, 2024 - 4:00 AM

CONCLUSIONS: Many EM residents reported concerns about COVID risks to themselves and their families. Although the rate of SI remained unchanged, more EM residents reported career regret during the COVID pandemic.

PubMed COVID-19 Clinical Care