PubMed COVID-19 Clinical Care

Increasing stage and depth of invasion (DOI) in patients with tongue cancer during the COVID-19 pandemic: A time series study

Wednesday, January 24, 2024 - 4:00 AM

CONCLUSION: COVID-19 has adverse effects on the diagnosis and treatment of tongue cancer. Also, it leads to advanced stages of the tumor and increases the depth of invasion of the cancer. Hence, it is important to plan correctly and appropriately for

Impact of vertical positioning on lung aeration among mechanically ventilated intensive care unit patients: a randomized crossover clinical trial

Wednesday, January 24, 2024 - 4:00 AM

CONCLUSION: This analysis did not find significant differences in lung aeration between the sitting and passive orthostasis groups. A randomized crossover clinical trial assessing the impact of vertical positioning on lung aeration in patients

Impact of vitamin D supplementation as COVID-19 vaccine adjuvant on sperm parameters and sex hormones in men with idiopathic infertility: Two separate pre-post studies

Wednesday, January 24, 2024 - 4:00 AM

CONCLUSION: Our results support vitamin D supplementation as an immune adjunct to COVID-19 vaccination for improving sperm parameters and hormone levels. COVID-19 vaccination is not harmful for male fertility potential, and vitamin D is an effective

Impact of COVID-19 Lockdown on Traumatic Bone Fracture Patterns and Hospital Outcomes in 1646 Elderly Patients: A Retrospective Study in Turkey

Wednesday, January 24, 2024 - 4:00 AM

BACKGROUND During the Coronavirus Disease-2019 (COVID-19) pandemic-related lockdowns, modifications in trauma-related behavior and other factors in the elderly population may have occurred. The present retrospective study aimed to compare outcomes

Identification of amentoflavone as a potent SARS-CoV-2 Mpro inhibitor: a combination of computational studies and in vitro biological evaluation

Wednesday, January 24, 2024 - 4:00 AM

Small-molecule inhibitors of SARS-CoV-2 M^(pro) that block the active site pocket of the viral main protease have been considered potential therapeutics for the development of drugs against SARS-CoV-2. Here, we report the identification of

Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19

Tuesday, January 23, 2024 - 4:00 AM

CONCLUSIONS: The findings indicate that long term dysfunction and immune cell remodeling of the CCS is induced by COVID-19, arising indirectly from oxidative stress and excessive activation of cardiac innate immune responses during infection, with

In Reply to "Using Immunoglobulin G Spike Antibodies as a Surrogate Marker for Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Additional Considerations"

Tuesday, January 23, 2024 - 4:00 AM

No abstract

Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program

Tuesday, January 23, 2024 - 4:00 AM

CONCLUSIONS: Ritlecitinib is well tolerated with an acceptable safety profile up to 24 months in patients aged ≥ 12 years with AA (video abstract and graphical plain language summary available).

Inequalities in health outcomes of SARS-CoV-2 infection by migration status in Barcelona, Spain

Tuesday, January 23, 2024 - 4:00 AM

CONCLUSION: Characteristics of migrant and native population differ greatly, which could be translated into different needs and health priorities. Native population had higher odds of IHM, but migrants were more likely to present to care symptomatic

Impact of the coronavirus (COVID-19) disease pandemic on healthy lifestyle behaviors in persons with and without disabilities in Qatar

Tuesday, January 23, 2024 - 4:00 AM

CONCLUSION: This study indicated that the pandemic has had a significant impact on the mental and physical health of people with and without disabilities in Qatar. These findings reveal how closely individuals with disabilities and their lifestyle