PubMed COVID-19 Clinical Care
1031 - 1040 of 3588 results found
Interleukin-6 and the determinants of severe COVID-19: A retrospective cohort study
Description
Cytokines, notably interleukin-6 (IL-6), increase considerably in patients with severe corona virus disease 2019 (COVID-19). This vigorous immune response may cause end-organ failure or death; hence, measuring IL-6 in the context of patient
Impact of covid-19 outbreak on the behavior of children and adolescents in the Kingdom of Bahrain
Description
With coronavirus disease-2019 (COVID-19) pandemic restrictions and lockdown, children and adolescents have experienced emotional and physical isolation from family and community members. This isolation has a negative impact on children's and
Influenza vaccine effectiveness against hospitalized SARS-CoV-2 infection
Description
CONCLUSION: The influenza vaccine provides a small degree of protection against SARS-CoV-2 infection across our study sites.
In vivo affinity maturation of murine B cells reprogrammed to express human antibodies
Description
CRISPR-edited murine B cells engineered to express human antibody variable chains proliferate, class switch, and secrete these antibodies in vaccinated mice. However, current strategies disrupt the heavy-chain locus, resulting in inefficient somatic
Insights into the epidemiology and clinical aspects of post-COVID-19 conditions in adult
Description
OBJECTIVES: While most individuals infected with COVID-19 recover completely within a few weeks, some continue to experience lingering symptoms. This study was conducted to identify and describe the clinical and subclinical manifestations of adult
Integrating population-level and cell-based signatures for drug repositioning
Description
Drug repositioning presents a streamlined and cost-efficient way to expand the range of therapeutic possibilities. Furthermore, drugs with genetic evidence are more likely to progress successfully through clinical trials towards FDA approval
Infection with COVID-19 is a risk factor for poor prognosis in patients with intracranial hemorrhage: A prospective observational cohort study
Description
This research aimed to explore the COVID-19 infection in the prognosis of patients with intracerebral hemorrhage (ICH), as well as analyzed the risk factors of the poor prognosis. This present prospective observational cohort study enrolled 136
Intranasal G5-BGG/pDNA vaccine elicits protective systemic and mucosal immunity against SARS-CoV-2 by transfecting mucosal dendritic cells
Description
Infectious disease pandemics, including the coronavirus disease 2019 pandemic, have heightened the demand for vaccines that provide both disease protection and transmission inhibition. Although parenteral vaccines induce robust systemic immunity
Is Non-operative Management of Appendicitis Inferior in the COVID-19 Era?
Description
CONCLUSIONS: This study demonstrates higher odds of mortality amongst non-operative management of appendicitis, and near equivalent outcomes for operative management regardless of COVID-19 status. We conclude that non-operative management of
