PubMed COVID-19 Clinical Care

Expression level of non-coding (MiR-155) gene as biomarker for severity of Coronaviruses infection among vaccinated and non-vaccinated Iraqi patients

Friday, March 22, 2024 - 4:00 AM

CONCLUSIONS: The miR-155 gene, overexpressed in SARS-CoV-2 patients, correlates with disease activity and severity, potentially serving as a biomarker for diagnosis and a potential therapeutic target.

Early treatment with fluvoxamine, bromhexine, cyproheptadine, and niclosamide to prevent clinical deterioration in patients with symptomatic COVID-19: a randomized clinical trial

Friday, March 22, 2024 - 4:00 AM

BACKGROUND: Repurposed drugs with host-directed antiviral and immunomodulatory properties have shown promise in the treatment of COVID-19, but few trials have studied combinations of these agents. The aim of this trial was to assess the effectiveness

Extreme Case of Surgical Port Metastasis in Ovarian Cancer

Friday, March 22, 2024 - 4:00 AM

Ovarian cancer accounts for more deaths than any other malignancy of the female reproductive system. Early diagnosis of this disease is difficult because there are no systematic opportunistic screening methods. At advanced stages, diagnostic

Excess mortality for acute myocardial infarction in the United States during the first two years of the COVID-19 pandemic

Friday, March 22, 2024 - 4:00 AM

No abstract

Evidence of Placental Villous Inflammation and Apoptosis in Third-Trimester Symptomatic SARS-CoV-2 Maternal Infection

Friday, March 22, 2024 - 4:00 AM

CONCLUSION: The presence of SARS-CoV-2 spike protein as well as altered inflammatory and apoptotic processes may indicate the presence of placental disturbance in third-trimester maternal COVID-19 infection. The lack of correlation between placental

Effects of Mother Voice on Physiological Response and Motor Nerve Development of Newborns with Maternal Separation Under the New Epidemic Situation

Friday, March 22, 2024 - 4:00 AM

CONCLUSION: Maternal voice intervention presents a promising strategy to diminish pain sensitivity and bolster neurological development in neonates separated from their mothers, particularly when family participatory nursing practices are constrained

Effect of 24-form simplified Tai Chi on executive inhibitory control of college students: a randomized controlled trial of EEG

Friday, March 22, 2024 - 4:00 AM

CONCLUSION: The pandemic-induced panic may impact frontal lobe brain activity in college students. TC training not only improves executive inhibitory control but may also enhance localized brain activity, suggesting its potential as a holistic

Exploiting high-energy hydration sites for the discovery of potent peptide aldehyde inhibitors of the SARS-CoV-2 main protease with cellular antiviral activity

Friday, March 22, 2024 - 4:00 AM

Small-molecule antivirals that prevent the replication of the SARS-CoV-2 virus by blocking the enzymatic activity of its main protease (Mpro) are and will be a tenet of pandemic preparedness. However, the peptidic nature of such compounds often

Exploring food security/insecurity determinants within Venezuela's complex humanitarian emergency

Friday, March 22, 2024 - 4:00 AM

INTRODUCTION: The complex humanitarian emergency that Venezuela has been going through for several years has deteriorated the quality of life of its citizens, deepened food insecurity in households and has promoted migratory movements of almost six

Extracellular vesicles derived from SARS-CoV-2 M-protein-induced triple negative breast cancer cells promoted the ability of tissue stem cells supporting cancer progression

Friday, March 22, 2024 - 4:00 AM

INTRODUCTION: SARS-CoV-2 infection increases the risk of worse outcomes in cancer patients, including those with breast cancer. Our previous study reported that the SARS-CoV-2 membrane protein (M-protein) promotes the malignant transformation of